DESCRIPTION: Oyster Mushroom Ferment Filtrate Filtrate delivers multi‑level skin support through its rich concentration of fermented polysaccharides, β‑glucans, and antioxidant compounds. These bio‑actives help strengthen the skin barrier, improve moisture retention, and reduce transepidermal water loss, resulting in smoother, more resilient skin. The ferment process enhances bioavailability, allowing the ingredient to provide immediate hydration while supporting long‑term barrier repair and improved skin comfort, even in sensitive or compromised skin conditions.
In addition to its moisturizing and barrier‑reinforcing properties, Oyster Mushroom Ferment Filtrate offers powerful antioxidant and soothing benefits. Naturally occurring ergothioneine and phenolic compounds help protect the skin from oxidative stress and environmental aggressors, while postbiotic metabolites calm irritation and reduce visible redness. Regular use supports a brighter, more even complexion and helps maintain skin firmness and elasticity, making this ingredient well suited for anti‑aging, sensitive‑skin, and radiance‑enhancing cosmetic formulations.
Composition & Key Bioactive Molecules
Oyster mushroom ferment filtrate contains a complex mixture of fermentation‑enhanced bioactives, including:
- β‑glucans (1,3/1,6‑β‑D‑glucans)
- Ergothioneine (antioxidant amino acid derivative)
- Ergosterol (pro‑vitamin D2 precursor)
- Phenolic acids (caffeic, ferulic, p‑coumaric)
- Polysaccharides & oligosaccharides
- Peptides & amino acids (released during fermentation)
- Trace minerals (Zn, Cu, Se)
- Organic acids (lactic, malic—depending on fermentation strain)
Fermentation increases:
- Molecular weight reduction → improved skin penetration
- Release of peptides → enhanced bioactivity
- Production of postbiotic metabolites → improved skin barrier support
MECHANISMS OF ACTION
Antioxidant Defense Activation: Reduces oxidative stress. Protects against pollution‑induced aging. Supports mitochondrial vitality
- Ergothioneine acts as a mitochondrial antioxidant, protecting keratinocytes from ROS.
- β‑glucans stimulate Nrf2 pathway activation, increasing endogenous antioxidant enzymes (SOD, catalase, glutathione peroxidase).
Barrier Repair & Moisturization: Improved hydration. Strengthened barrier. Reduced dryness and irritation
- β‑glucans form a biopolymer film, reducing TEWL.
- Fermentation releases short‑chain polysaccharides that enhance corneocyte cohesion.
- Organic acids help maintain acid mantle integrity.
Anti‑Inflammatory & Soothing Activity: Reduces redness. Calms sensitive skin. Suitable for rosacea‑prone and reactive skin
- Mushroom polysaccharides modulate NF‑κB signaling, reducing pro‑inflammatory cytokines (IL‑6, TNF‑α).
- Postbiotic metabolites support microbiome balance.
Brightening & Anti‑Pigmentation: More even skin tone. Reduction in dullness. Prevention of dark spot formation.
- Phenolic acids inhibit tyrosinase activity.
- Ergothioneine reduces oxidation of melanin precursors.
Anti‑Aging & Firming: Improved elasticity, Reduction in fine lines, Enhanced dermal density
- β‑glucans stimulate fibroblast proliferation and collagen synthesis.
- Antioxidant protection reduces collagen degradation via MMP inhibition.
BENEFITS
- Strengthens the skin barrier for enhanced protection.
- Improves moisture retention and reduces water loss for smoother skin.
- Provides immediate hydration and supports long-term barrier repair.
- Contains antioxidants that protect against oxidative stress and environmental damage.
- Soothes irritation and reduces visible redness.
- Supports a brighter, more even complexion.
- Helps maintain skin firmness and elasticity.
- Supports a healthy skin microbiome
- Suitable for anti-aging, sensitive skin, and radiance-enhancing formulations.
- Suitable for leave‑on and rinse‑off products.
- Non‑GMO and vegan
- No known sensitization issues at cosmetic concentrations.
Compatibility and Synergies: D-panthenol, niacinamide, Proxylane, Japanese Sake, Banana Mucin, Sacharride Isomerate, Blackberry Rice Ferment, Sea Cucumber, Purslane, Goji Polysaccharides, Arto-Radiance.
Avoid
- Very low pH (<3) for long periods (may degrade polysaccharides)
- Strong oxidizers
- High ethanol (>20%)
APPLICATION: Toners, Essences, lotions, creams, masks, scalp serums, hair conditioners, cleansers, etc

FORMULATION GUIDELINES
| INCI Name | Pleurotus Sajo-Caju Ferment Filtrate |
| Use Rate | 1–5% (standard), up to 10% for intensive treatments (Toners/Essenses 1.0 – 3.0%, Serums: 2.0 – 5.0%, Moisturizers: 1.0 – 5.0%, Masks: 3.0 – 10.0%, Scalp care: 1.0 – 5.0% |
| Solubility | Water‑soluble |
| pH Stability | 4.5 – 6.5 |
| Temperature Tolerance | Avoid temperatures above 40°C |
| Appearance | Clear to slightly opalescent liquid |
| Odor | Mild, slightly earthy |
| Production Method | Aqueous extraction followed by lactic acid bacteria, yeast, or enzymatic fermentation to enhance bioavailability |
| Storage | Store in a cool, dark and dry place. Fermented extracts may darken slightly over time—normal for phenolic‑rich materials. |


This is a cosmetic raw material and is meant for external use only in cosmetic formulations. As with all of our materials, it should not be taken internally. Treasure Actives is not responsible for product compatibility. We advise everyone to test ingredients for performance, compatibility, and safety prior to committing to larger quantities. Keep all products out of reach of children. For more information, please see our terms and conditions page.
