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DESCRIPTION: Salmon DNA (PDRN) is a low molecular weight polymer extracted from Salmons with excellent performance in wound healing anti-inflammation. More comely known by the trade name, Rejuran, it works through the stimulation of growth factors and increased microcirculation. It also scavenges free radicals and prevents the exaggerated response of inflammatory cytokines in the skin that cause such issues as excessive skin darkening, etc. Salmon DNA PDRN mimics extracellular nucleotides, improves skin hydration, reduces fine lines and wrinkles, improves skin tone, improves the skin’s barrier function, improves skin texture, and stimulates the regeneration of epidermal and dermal skin cells, with long-lasting results.

Salmon DNA – PDRN is a nature-identical pure peptide (meaning it is synthetic but matches the PDRN extracted from salmon sperm). There is a lot of research on PDRN that shows that it is helpful in wound healing associated with diabetes, and foot ulcers, prevention of scars and reviving skin tissues through stimulation of Adenosine A2A receptors.

pdrn mechanism of action
PDRN mechanism of action

In hair care, Salmon DNA Peptide (PDRN) can also stimulate hair growth.

FEATURES

  • Salmon DNA PDRN increases the metabolic activity of fibroblasts (cells in the dermis responsible for producing collagen elastin and glycosaminoglycans.
  • It makes the skin stronger and younger-looking.
  • It improves skin elasticity by boosting the skin’s structural support system, stimulating the production of extracellular matrix proteins.
  • Provides building blocks for DNA synthesis – Salmon DNA are made of short, low molecular strands of linked deoxyribonucleotides, which are the building blocks of DNA.
  • Activates adenosine receptors.
  • Reduces UV-induced inflammation and damage.
  • Prevents skin sagging.
  • Treats acne scars, stretch marks and enlarges pores
  • Prevents hyperpigmentation and dull skin.
  • Treats dark eye circles.
  • Skin energizing, revitalizing and rejuvenating.
  • Research shows that salmon DNA is very safe and compatible with human skin.

APPLICATION: Serums, ampoules, creams, lotions, conditioners, treatment products, etc targeted towards anti-ageing, skin rejuvenation, and wound healing, etc.

HOW TO USE

INCI: Aqua (and) Propanediol (and) DMDM Hydantoins (and) DNA

Solubility: Water

Use Rate: 1.0 – 20.0% Recommended at 10.0%

pH Stability Range: 3.5 – 6.5

Temperature Tolerance: Avoid temperatures above 40°C

Grade: Cosmetic Grade

Appearance: Clear, colourless to slightly opaque liquid.

Assay: 5000ppm

Molecular Weight: 50 – 1500 kDa

Storage: Store in a cool, dark, and dry place. Refrigerate for long-term storage.

VeganNature identical

This is a cosmetic raw material and is meant for external use only in cosmetic formulations.  As with all of our materials, it should not be taken internally. Treasure Actives is not responsible for product compatibility. We advise everyone to test ingredients for performance, compatibility, and safety prior to committing to larger quantities. Keep all products out of reach of children. For more information, please see our terms and conditions page.

 

 

 

 

 

Polydeoxyribonucleotide (PDRN) is a safe approach to induce therapeutic angiogenesis in peripheral artery occlusive disease and diabetic foot ulcers. Altavilla D et al.

The effect of PDRN, an adenosine receptor A2A agonist, on the healing of chronic diabetic foot ulcers: clinical trial results. Squadrito F et al

Scar Prevention and Enhanced Wound Healing Induced by Polydeoxyribonucleotidein a Rat Incisional Wound-Healing Model. Jeong W et al

Polydeoxyribonucleotiderestores blood flow in an experimental model of ischemic skin flaps. Polito F et al

Pharmacological Activity and Clinical Use of PDRN Francesco Squadrito et al

Effect of DNA from salmon milt on human skin conditions T.-F. Hsu et al

A Phase III, Randomized, Double-Blind, Matched-Pairs, Active-Controlled Clinical Trial and Preclinical Animal Study to Compare the Durability, Efficacy and Safety between Polynucleotide Filler and Hyaluronic Acid Filler in the Correction of Crow’s Feet: A New Concept of Regenerative Filler Chang Sik Pak et al

Therapeutic Efficacy of 1,927-nm Fractionated Thulium Laser Energy and Polydeoxyribonucleotide on Pattern Hair Loss Sung Bin Cho et al

Salmon DNA – PDRN

A powerful anti-ageing, skin rejuvenating and skin-healing activator 

NGN9,544.00NGN27,000.00